Which fungal infection is often seen in immunocompromised individuals?

Candidiasis is a fungal infection that is particularly common in immunocompromised individuals. This infection is caused by Candida species, which are yeasts typically found in the human microbiome. In healthy individuals, these organisms usually do not cause disease; however, in those with weakened immune systems—such as patients with HIV/AIDS, those undergoing chemotherapy, or individuals on immunosuppressive medications—Candida can overgrow and lead to infections.

Candidiasis can present in various forms, including superficial infections like oral thrush and vulvovaginal candidiasis, as well as systemic infections that can affect the bloodstream and internal organs. The predisposition of immunocompromised individuals to Candida infections is linked to their diminished ability to control the growth of these yeasts, leading to increased risk and severity of the disease.

While other fungal infections like Histoplasmosis, Aspergillosis, and Cryptococcus also target immunocompromised patients, Candidiasis is more prevalent due to the ubiquity of Candida species in human environments and the body. Therefore, its occurrence is often more directly associated with conditions that compromise the immune system.