What should the nurse's priority intervention be for a client with multiple myeloma and a fever of 102.2°F?

The priority intervention for a client with multiple myeloma presenting with a fever of 102.2°F is to administer the prescribed antipyretic and notify the charge nurse or primary healthcare provider. This is because a fever in a patient with multiple myeloma can indicate an infection, which is a significant concern in immunocompromised individuals.

Administering an antipyretic serves to reduce fever and improve patient comfort while potentially assisting in the management of an underlying infection. Additionally, notifying the charge nurse or primary healthcare provider is crucial as it facilitates timely assessment and intervention, ensuring that the patient's condition is closely monitored and managed. This approach reflects the prioritization of addressing potentially life-threatening complications associated with multiple myeloma, such as infections due to their immunosuppressed state.

Monitoring vital signs, increasing fluid intake, and assessing for other symptoms are all relevant actions but do not address the immediate need to manage fever and possible infection, which could lead to more severe consequences if not handled promptly.